The genetic code and the origin of life

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Landes Bioscience/ ;
Pub. Date:
Early Thoughts on RNA and the Origin of Life The full impact of the essential role of the nucleic acids in biological systems was forcefully demonstrated by the research community in the 1950s. Although Avery and his collaborators had identified DNA as the genetic material responsible for the transformation of bacteria in 1944, it was not until the early 1950s that the Hershey-Chase experiments provided a more direct demonstration of this role. Finally, the structural DNA double helix proposed by Watson and Crick in 1953 clearly created a structural frame­ work for the role of DNA as both information carrier and as a molecule that could undergo the necessary replication needed for daughter cells. Research continued by Kornberg and his colleagues in the mid-1950s emphasized the biochemistry and enzymology of DNA replication. At the same time, there was a growing interest in the role of RNA. The 1956 dis­ covery by David Davies and myself showed that polyadenylic acid and polyuridylic acid could form a double-helical RNA molecule but that it differed somewhat from DN A A large number of experiments were subsequendy carried out with synthetic polyribonucleotides which illustrated that RNA could form even more complicated helical structures in which the specificity of hydrogen bonding was the key element in determining the molecular conformation. Finally, in I960,1 could show that it was possible to make a hybrid helix.
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Grouped Work ID 76d0cde4-7d87-1100-f9da-a6710d3f17ef
Grouping Title genetic code and the origin of life
Grouping Author lluís ribas de pouplana
Grouping Category book
Last Grouping Update 2018-10-10 01:06:21AM
Last Indexed 2019-03-24 05:06:55AM

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auth_author2 Ribas de Pouplana, Lluís.
author2-role Ribas de Pouplana, Lluís., SpringerLink (Online service)
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isbn 9780387268873
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literary_form Non Fiction
literary_form_full Non Fiction
owning_library_ccu Colorado Christian University Online
owning_location_ccu CCU Electronic Resources
primary_isbn 9780387268873
publishDate 2004
record_details external_econtent:ils:.b29505070|eBook|eBook||English|Landes Bioscience/ ;|[2004]|253 pages : illustrations ; 24 cm.
recordtype grouped_work
Bib IdItem IdGrouped StatusStatusLocally OwnedAvailableHoldableBookableIn Library Use OnlyLibrary OwnedHoldable PTypesBookable PTypesLocal Url
external_econtent:ils:.b29505070 .i71721514 Available Online Available Online false true false false false true
series Molecular biology intelligence unit
series_with_volume Molecular biology intelligence unit|
subject_facet Code génétique, Electronic books, Evolution, Molecular, Evolutionary genetics, Genetic Code, Genetic code, Genoom, Génétique évolutive, Leven, Oorsprong
title_display The genetic code and the origin of life
title_full The genetic code and the origin of life [electronic resource] / [edited by] Lluís Ribas de Pouplana
title_short The genetic code and the origin of life
topic_facet Code génétique, Evolution, Molecular, Evolutionary genetics, Genetic Code, Genetic code, Genoom, Génétique évolutive, Leven, Oorsprong