Integrative physiology in the proteomics and post-genomics age

Book Cover
Publisher:
Humana Press,
Pub. Date:
[2005]
Language:
English
Description
There is a perception in the scientific community that the discipline of Physiology is in crisis, or at least, in a phase of profound transition and change. At the root of the problem is confusion between objectives (the biological questions to be solved) and the methods and technologies to be applied. Traditionally, ever since Claude Bernard's concept of the "milieu interieur," Physiology was an integrative science with the prime concern of studying regulatory mechanisms leading to adaptation and homeostasis in the presence of challenges from a dynamic internal and external environment. This study of control mechanisms can be applied on any level of fu- tion whether subcellular, cellular, and organ, but reaches its highest level of complexity with the functioning of the body as a whole and its interaction with the external environment. This involves the determination of the interaction of genetic with environmental factors and the resulting integrated body adaptation. It might seem obvious that in the pursuit of these questions any appropriate combination of techniques on any organizational level could be used. Yet the advent of molecular techniques has resulted in a preoccupation with the problems and challenges inherent in these techniques, sometimes at the expense of the original perspectives and concepts. The many new mechanisms that have been discovered at the molecular level, as well as their economical exploitation, have contributed to a climate of reductionism.
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ISBN:
9781588293152
9781592599257
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Grouping Information

Grouped Work ID 56440941-aa22-bc01-a52c-3fdb8a64dfac
Grouping Title integrative physiology in the proteomics and post genomics age
Grouping Author wolfgang walz
Grouping Category book
Last Grouping Update 2019-01-08 01:08:44AM
Last Indexed 2019-03-18 04:36:11AM

Solr Details

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auth_author2 Walz, Wolfgang.
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display_description This collection of articles by internationally recognized researchers highlights the major questions and accomplishment of modern physiological research and demonstrates that modern molecular methods can well be incorporated and strengthen the original integrative perspectives of physiology set out by Claude Bernard's concept of the "milieu interieur." Among the critical issues discussed are the place of functional genomics in regulatory physiology, the role of model systems in integrative physiology, the function of neural circuits in behavior and consciousness, and the influence of.
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subject_facet Biologie moléculaire, Biomédecine, Electronic books, Genomics, Genomik, Génomique, Mikrobiologie, Molecular Biology, Molecular biology, Natural history, Physiologie, Physiologie expérimentale, Physiology, Physiology, Experimental, Proteomics, Protéomique, Research, SCIENCE -- Life Sciences -- Anatomy & Physiology, Science, Sciences de la vie
title_display Integrative physiology in the proteomics and post-genomics age
title_full Integrative physiology in the proteomics and post-genomics age / edited by Wolfgang Walz
title_short Integrative physiology in the proteomics and post-genomics age
topic_facet Anatomy & Physiology, Biologie moléculaire, Biomédecine, Genomics, Genomik, Génomique, Life Sciences, Mikrobiologie, Molecular Biology, Molecular biology, Natural history, Physiologie, Physiologie expérimentale, Physiology, Physiology, Experimental, Proteomics, Protéomique, Research, SCIENCE, Science, Sciences de la vie